FB2024_03 , released June 25, 2024
Allele: Dmel\fwsev.Tag:HA
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General Information
Symbol
Dmel\fwsev.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0295051
Feature type
allele
Associated gene
Dmel\fw
Associated Insertion(s)
Carried in Construct
P{sev-fw.HA}
Key Links
Transgenic product class
wild_type
(Chin and Mlodzik, 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Chin and Mlodzik, 2013)
Mutagen
in vitro construct
(Chin and Mlodzik, 2013)
Progenitor genotype
Carried in construct
P{sev-fw.HA}
Cytology
Description

A sev enhancer drives expression of fw tagged with Tag:HA.

(Chin and Mlodzik, 2013)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
fw
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of two copies of fwsev.T:Ivir\HA1 results in planar cell polarity defects in the eye, with many symmetrical ommatidia and some photoreceptor cell loss.

      (Chin and Mlodzik, 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Statement
      Reference

      fwsev.Tag:HA has abnormal planar polarity phenotype, non-enhanceable by Vangstbm-6/Vang[+]

      (Chin and Mlodzik, 2013)
      Suppressed by
      Statement
      Reference

      fwsev.Tag:HA has abnormal planar polarity phenotype, suppressible | partially by fz[+]/fz21

      (Chin and Mlodzik, 2013)

      fwsev.Tag:HA has abnormal planar polarity phenotype, suppressible | partially by stan[+]/stanE59

      (Chin and Mlodzik, 2013)
      NOT suppressed by
      Statement
      Reference

      fwsev.Tag:HA has abnormal planar polarity phenotype, non-suppressible by Vangstbm-6/Vang[+]

      (Chin and Mlodzik, 2013)
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      fwsev.Tag:HA has ommatidium phenotype, non-enhanceable by Vangstbm-6/Vang[+]

      (Chin and Mlodzik, 2013)
      Suppressed by
      Statement
      Reference

      fwsev.Tag:HA has ommatidium phenotype, suppressible | partially by fz[+]/fz21

      (Chin and Mlodzik, 2013)

      fwsev.Tag:HA has ommatidium phenotype, suppressible | partially by stan[+]/stanE59

      (Chin and Mlodzik, 2013)
      NOT suppressed by
      Statement
      Reference

      fwsev.Tag:HA has ommatidium phenotype, non-suppressible by Vangstbm-6/Vang[+]

      (Chin and Mlodzik, 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      fz21/+ partially suppresses the planar cell polarity defects in the eye caused by expression of two copies of fwsev.T:Ivir\HA1.

      Vangstbm-6/+ has no effect on the planar cell polarity phenotype in the eye caused by expression of two copies of fwsev.T:Ivir\HA1.

      stanE59/+ strongly suppresses the planar cell polarity defects in the eye caused by expression of two copies of fwsev.T:Ivir\HA1.

      (Chin and Mlodzik, 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fwsev.T:Ivir\HA1
      fwsev.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)