UASt regulatory sequences drive expression of Hsap\L1CAM which lacks part of the intracellular domain including the FIGQY motif.
Expression of Hsap\L1CAMScer\UAS.1180 under the control of Scer\GAL4OK307 has no effect on Giant Fibre (GF) synapse functionality.
Hsap\L1CAMUAS.1180/Scer\GAL4shot-OK307 is a non-suppressor of abnormal neurophysiology | adult stage phenotype of Nrg180ΔFIGQY, Nrgl4
Hsap\L1CAMUAS.1180/Scer\GAL4shot-OK307 is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of Nrg180ΔFIGQY, Nrgl4
Hsap\L1CAMUAS.1180/Scer\GAL4shot-OK307 is a non-suppressor of giant fiber neuron | adult stage phenotype of Nrg180ΔFIGQY, Nrgl4
Hsap\L1CAMUAS.1180/Scer\GAL4shot-OK307 is a non-suppressor of adult neuromuscular junction phenotype of Nrg180ΔFIGQY, Nrgl4
Expression of Hsap\L1CAMScer\UAS.1180 under the control of Scer\GAL4OK307 does not suppress the Giant Fibre (GF)-Trochanteral Muscle (TTM) synapse functional and morphological defects seen in flies expressing Nrg180ΔFIGQY in a Nrgl4 mutant background.