FB2024_03 , released June 25, 2024
Allele: Dmel\brkΔ3RGM
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General Information
Symbol
Dmel\brkΔ3RGM
Species
D. melanogaster
Name
FlyBase ID
FBal0290698
Feature type
allele
Associated gene
Dmel\brk
Associated Insertion(s)
TI{TI}brkΔ3RGM
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
site specific recombination
(Upadhyai and Campbell, 2013)
cre recombinase
(Upadhyai and Campbell, 2013)
Progenitor genotype
brkKO
(Upadhyai and Campbell, 2013)
Associated Insertion(s)
TI{TI}brkΔ3RGM
Cytology
Description

Re-integration of sequence using the attP site present in brkKO, resulting in a mutated brk gene (the 3R and GiM domains have been mutated) at the native locus (with in addition an attR site in the 5'UTR and a loxP site in the 3'UTR).

(Upadhyai and Campbell, 2013)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants show loss of ventral denticles.

      Homozygous clones result in outgrowths in the wing.

      (Upadhyai and Campbell, 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      brkΔ3RGM
      (Upadhyai and Campbell, 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)