FB2024_03 , released June 25, 2024
Allele: Ncra\QFQF2w.αTub84B
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General Information
Symbol
Ncra\QFQF2w.αTub84B
Species
N. crassa
Name
FlyBase ID
FBal0288664
Feature type
allele
Associated gene
Ncra\QF
Associated Insertion(s)
Carried in Construct
P{αTub84B-QF2w.P}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Riabinina et al., 2015, Riabinina and Potter, 2013.10.1)
Progenitor genotype
Carried in construct
P{αTub84B-QF2w.P}
Cytology
Description

αTub84B regulatory sequences control expression of a QF2w driver (a derivative of QF in which the middle domain is completely deleted and the activation domain is mutated to reduce activity by altering the charge on the C-terminus).

(Riabinina et al., 2015)

αTub84B regulatory sequences control expression of a QF2w driver (this is a weaker transactivator and shows slightly less toxicity compared to the QF2 driver).

(Riabinina and Potter, 2013.10.1)
Allele components
Component
Use(s)
Regulatory region(s)
αTub84B
Encoded product / tool
QF2w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage -- adult stage
      organism | ubiquitous
      (Riabinina et al., 2015)
      Additional Information
      Statement
      Reference

      NcraQFQF2w.αTub84B drives ubiquitous expression; expression is weaker than that of NcraQFQF2.αTub84B.

      (Riabinina et al., 2015)
       
      Marker for
      Reflects expression of
      αTub84B
      (Riabinina et al., 2015)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ncra\QFQF2w.αTub84B
      Name Synonyms
      Secondary FlyBase IDs
        References (3)