FB2024_03 , released June 25, 2024
Allele: Dmel\DeltaΔICD2.UAS.Tag:V5,Tag:polyHis
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General Information
Symbol
Dmel\DeltaΔICD2.UAS.Tag:V5,Tag:polyHis
Species
D. melanogaster
Name
FlyBase ID
FBal0284714
Feature type
allele
Associated gene
Dmel\Delta
Associated Insertion(s)
Carried in Construct
P{UAS-Delta-V5-His.ΔICD2}
Key Links
Transgenic product class
inframe_deletion
(Daskalaki et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Daskalaki et al., 2011)
Mutagen
in vitro construct
(Daskalaki et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-Delta-V5-His.ΔICD2}
Cytology
Description

UAS regulatory sequences drive expression of Dl coding sequences where the second intracellular domain has been deleted, tagged at the C-terminal with Tag:V5 and Tag:polyHis.

(Daskalaki et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Delta
Tagged with
Tag:polyHis
Tag:V5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of DlΔICD2.Scer\UAS.T:SV5\V5,T:Zzzz\His6 under the control of the ubiquitous driver Scer\GAL4mat.αTub67C.T:Hsim\VP16 restores N signalling in DlRevF10 SerRX106 mutant clones, leading to individualised sensory organ precursors. These are often spaced apart from each other, suggesting that a low level of lateral inhibition is still taking place.

      (Daskalaki et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DeltaΔICD2.UAS.Tag:V5,Tag:polyHis
      DlΔICD2.Scer\UAS.T:SV5\V5,T:Zzzz\His6
      DlΔICD2.UAS.Tag:V5,Tag:polyHis
      Name Synonyms
      Secondary FlyBase IDs
        References (1)