Nucleotide substitution: C640T.
Amino acid replacement: R214term.
The mutation is predicted to truncate the protein 24 amino acids from the end.
C2727410T
C640T
R214term | vilya-PA
R214term
vilya826 females show frequent meiotic chromosome segregation errors, as assessed by X-chromosome non-disjunction.
Homozygous females show 41.1% X chromosome nondisjunction and 31.8% 4th chromosome nondisjunction.
vilya826 is an enhancer of abnormal meiotic cell cycle | recessive | female phenotype of c(3)GccΔ3
vilya826 is a suppressor of female sterile phenotype of okrAA/okrRU
vilya826 is rescued by Scer\GAL4VP16.nanos.UTR/vilyaUASp.Tag:HA
Expression of vilyaScer\UAS.P\T.T:Ivir\HA1 in the germline fully rescues the chromosome segregation defects seen in vilya826 homozygotes.