FB2024_03 , released June 25, 2024
Allele: Dmel\cv-2F1-42
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General Information
Symbol
Dmel\cv-2F1-42
Species
D. melanogaster
Name
FlyBase ID
FBal0283091
Feature type
allele
Associated gene
Dmel\cv-2
Associated Insertion(s)
TI{TI}cv-2F1-42
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ends-in gene targeting
(Serpe et al., 2008)
FLPase
(Serpe et al., 2008)
I-SceI
(Serpe et al., 2008)
Progenitor genotype
cv-2F1-42
(Serpe et al., 2008)
Associated Insertion(s)
TI{TI}cv-2F1-42
Cytology
Description

Partial duplication of the cv-2 locus and insertion of a premature stop codon at residue I293 of the CR4 domain in exon six of the first copy. A w+mW.hs marker has also been inserted as part of the targeting event.

(Serpe et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      cv-2F1-42 mutant flies are homozygous viable but significant lethality is seen at 18[o]C. Adult wings lack the posterior cross vein and sometimes the anterior cross vein and the tips of some longitudinal veins.

      cv-2F1-42 mutant clones restricted to one wing epithelium (either dorsal or ventral) do not show any posterior cross vein defects.

      (Serpe et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cv-2F1-42
      (Serpe et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)