Scer\GAL4DJ717/drdUAS.cSa partially rescues drdlwf
drdUAS.cSa/Scer\GAL4hs.PB partially rescues drdlwf
Expressing drdUAS.cSa under the control of Scer\GAL4drd-MI15121-TG4.1 (the intrinsic Gal4 driver of drdMI15121-TG4.1) rescues adult mortality in drdMI15121-TG4.1/drdlwf flies.
Expressing drdUAS.cSa under the control of Scer\GAL4DJ626 rescues adult mortality, the presence of holes in the brain, peritrophic membrane formation and defecation rates in drdlwf/drdlwf adult flies.
Expressing drdUAS.cSa under the control of Scer\GAL4DJ717 rescues the presence of holes in the brain, partially rescues adult mortality and fails to rescue peritrophic membrane formation and defecation rates in drdlwf/drdlwf adult flies.
Limiting expression of drdUAS.cSa under the control of Scer\GAL4hs.PB to metamorphosis by exposing pupae to the permissive temperature rescues adult mortality, but not peritrophic membrane formation in drdlwf/drdlwf adult flies.
The short lived phenotype seen in drdlwf animals is rescued by expression of drdScer\UAS.cSa under the control of Scer\GAL4Act5C.PI.
Temperature shift experiments using flies carrying drdScer\UAS.cSa and Scer\GAL4hs.PB indicate that expression of drdScer\UAS.cSa during the final 48 hours of metamorphosis completely rescues the short lived phenotype seen in drdlwf animals.