FlyBase Allele Report: Dmel\Usp47[C405A.UAS]

General Information

Symbol

Dmel\Usp47^C405A.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0280594

Feature type

allele

Associated gene

Dmel\Usp47

Associated Insertion(s)

Carried in Construct

P{UAS-Usp47.C405A}

Key Links

Transgenic product class

missense_variant

(Bajpe et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Bajpe et al., 2008)

Mutagen

in vitro construct

(Bajpe et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-Usp47.C405A}

Cytology

Description

UASt regulatory sequences drive expression of a mutant Usp47 cDNA in which the cysteine at amino acid 405 has been replaced by alanine.

(Bajpe et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Usp47

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Eye development appears normal in flies expressing Ubp64E^{C405A.Scer\UAS} under the control of Scer\GAL4^GMR.PF.

(Bajpe et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of visible phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of ommatidium | adult stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of interommatidial bristle phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of eye disc | pupal stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of ommatidium | pupal stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of cone cell | pupal stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^C405A.UAS/Scer\GAL4^GMR.PF is a non-enhancer of photoreceptor neuron | pupal stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Ubp64E^{C405A.Scer\UAS} does not enhance the adult eye phenotypes seen when ttk^69.Scer\UAS is expressed under the control of Scer\GAL4^GMR.PF. The cone cell and photoreceptor disruption seen in the ommatidia of pupal eye discs is also unaffected.

(Bajpe et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ubp64E^{C405A.Scer\UAS}

Usp47^{C405A.Scer\UAS}

Usp47^C405A.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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