FlyBase Allele Report: Dmel\Usp47[UAS.cBa]

General Information

Symbol

Dmel\Usp47^UAS.cBa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Bajpe

FlyBase ID

FBal0280593

Feature type

allele

Associated gene

Dmel\Usp47

Associated Insertion(s)

Carried in Construct

P{UAS-Usp47.B}

Key Links

Transgenic product class

cDNA

(Bajpe et al., 2008)

wild_type

(Bajpe et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Bajpe et al., 2008)

wild_type

(Bajpe et al., 2008)

Mutagen

in vitro construct

(Bajpe et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-Usp47.B}

Cytology

Description

UASt regulatory sequences drive expression of a wild type Usp47 cDNA.

(Bajpe et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Usp47

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Phenotype Manifest In

cone cell | pupal stage, with Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

eye, with Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

eye disc | pupal stage, with Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

interommatidial bristle, with Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

ommatidium | adult stage, with Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

photoreceptor neuron | pupal stage, with Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Detailed Description

Statement

Reference

Flies expressing Ubp64E^Scer\UAS.cBa under the control of Scer\GAL4^GMR.PF have a rough eye phenotype. As well as distorted eye morphology and irregular arrangement of the ommatidia, a clear reduction in the number of ommatidial bristles is seen. The ommatidia in 40hr old pupal eye discs are disorganised and frequently contain five cone cells, rather than the usual four. Photoreceptor cell formation is also inhibited, leading to fewer than the normal complement of eight photoreceptors.

(Bajpe et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has visible phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Enhancer of

Statement

Reference

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has eye phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has ommatidium | adult stage phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has interommatidial bristle phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has eye disc | pupal stage phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has ommatidium | pupal stage phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has photoreceptor neuron | pupal stage phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Scer\GAL4^GMR.PF, Usp47^UAS.cBa has cone cell | pupal stage phenotype, enhanceable by ttk^69.UAS/Scer\GAL4^GMR.PF

(Bajpe et al., 2008)

Enhancer of

Statement

Reference

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of interommatidial bristle phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of eye disc | pupal stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of ommatidium | pupal stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of photoreceptor neuron | pupal stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of cone cell | pupal stage phenotype of ttk^69.UAS

(Bajpe et al., 2008)

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Usp47^UAS.cBa/Scer\GAL4^GMR.PF is an enhancer of ommatidium | adult stage phenotype of Scer\GAL4^GMR.PF, ttk^69.UAS

(Bajpe et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of ttk^69.Scer\UAS and Ubp64E^Scer\UAS.cBa under the control of Scer\GAL4^GMR.PF causes dramatically defective eye development, more severe than is seen when either transgene is expressed alone. The cone cell disruption seen in the ommatidia of pupal eye discs is also enhanced, as is the disruption to the photoreceptor pattern.

(Bajpe et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Ubp64E^Scer\UAS.cBa

Usp47^Scer\UAS.cBa

Usp47^UAS.cBa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Bajpe

Secondary FlyBase IDs

References (1)

Report Sections

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