FB2024_03 , released June 25, 2024
Allele: Dmel\sggED6584
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General Information
Symbol
Dmel\sggED6584
Species
D. melanogaster
Name
FlyBase ID
FBal0277519
Feature type
allele
Associated gene
Dmel\sgg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(1)ED6584
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygous sggED6584 mutant flies are lethal.

        Most of the eggs derived from mothers carrying sggED6584 mutant germline clones are unable to complete meiosis. 91.9% of eggs show an anaphase I-arrested chromosome configuration. Metaphase I arrest appears normal in the mature oocytes.

        (Takeo et al., 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        sggED6584 is rescued by sggUASp.cTa

        (Takeo et al., 2012)
        Comments

        Expression of sggScer\UAS.P\T.cTa under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 rescues the meiotic defects seen in sggED6584 mutant germline clones.

        (Takeo et al., 2012)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        sggED6584
        Name Synonyms
        Secondary FlyBase IDs
          References (1)