UASt regulatory sequences drive expression of a 500bp inverted repeat.
Flies expressing NKCCNIG.2509R under the control of Scer\GAL4tim.PE (but not Scer\GAL4qsm-NP6258 or Scer\GAL4qsm-NP6258) exhibit short-period locomotor rhythms in constant dim white light, in contrast to control flies which largely show arrhythmic behavior in these conditions. These flies do not exhibit any difference in locomotor rhythms when kept in constant darkness, as compared to controls.
The l-LNv neurons in flies expressing NKCCNIG.2509R under the control of Scer\GAL4Pdf.PU exhibit a hyperpolarized resting membrane potential, and a reduced spontaneous firing rate during the daytime, but not during the night, as compared to wild type; these neurons also fail to respond to blue light stimulus, in contrast to wild type.
NKCCNIG.2509R, Scer\GAL4tim.PE is a suppressor | partially of abnormal neurophysiology | adult stage phenotype of Scer\GAL4tim.PE, qsmGD4817
NKCCNIG.2509R, Scer\GAL4tim.PE is a suppressor | partially of l-LNv neuron | adult stage phenotype of Scer\GAL4tim.PE, qsmGD4817
Co-expression of NKCCNIG.2509R partially suppresses the increased spontaneous firing rate of l-LNv neurons in flies expressing qsmGD4817 under the control of Scer\GAL4tim.PE.