A 10.2 kb genomic fragment containing the entire mle coding region and its flanking sequences lacking the region encoding amino acids 326-378 corresponding to the minimal trans-activation domain (MTAD) of mle.
lethal - all die before end of larval stage, with mle1
some die during third instar larval stage, with mle1
mle1 mutants with the mleΔMTAD transgene die during late larval stages.
mleΔMTAD fails to rescue mle1
mle+t10.2 fails to rescue the lethality of mle1. The mutant die during late larval stages.