FB2024_03 , released June 25, 2024
Allele: Dmel\CG3329844-5
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General Information
Symbol
Dmel\CG3329844-5
Species
D. melanogaster
Name
FlyBase ID
FBal0269071
Feature type
allele
Associated gene
Dmel\CG33298
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Ma et al., 2012)
    Mutagen
    Progenitor genotype
    P{GSV6}GdiGS14514
    (Ma et al., 2012)
    Cytology
    Description

    Imprecise excision of P{GSV6}GdiGS14514 resulting in a deletion of the second exon and part of the third exon, including the start codon, of CG33298. This deletion includes the coding region (nt 1-382) for the first 128 amino acids of CG33298. The next available in-frame start codon is 524 nt away from the deletion and starts at amino acid 303. Therefore, CG3329844-5 might produce a truncated protein lacking the N-terminal 302 amino acids.

    (Ma et al., 2012)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        CG3329844-5 homozygotes or CG3329844-5/Df(2L)Exel6022 flies are viable and show no discernible phenotypes.

        (Ma et al., 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        CG3329844-5/CG33298[+] is a suppressor | partially of wing phenotype of OsbpUAS.cMa, Scer\GAL4CCAP.PP

        (Ma et al., 2012)

        CG3329844-5/CG33298[+] is a suppressor of Golgi apparatus phenotype of OsbpUAS.cMa, Scer\GAL4CCAP.PP

        (Ma et al., 2012)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        CG3329844-5/+ suppresses the uninflated wing phenotype of Scer\GAL4Ccap.PP, OsbpScer\UAS.cMa flies.

        CG3329844-5/+ partially suppresses the Golgi morphology phenotype caused by Scer\GAL4Ccap.PP-mediated expression of OsbpScer\UAS.cMa.

        (Ma et al., 2012)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        CG3329844-5
        (Ma et al., 2012)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)