FB2024_03 , released June 25, 2024
Allele: Dmel\ftΔECD.UAS.Tag:HA
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General Information
Symbol
Dmel\ftΔECD.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0267981
Feature type
allele
Associated gene
Dmel\ft
Associated Insertion(s)
Carried in Construct
P{UAS-ft.ΔECD.HA}
Key Links
Transgenic product class
inframe_deletion
(Matakatsu and Blair, 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Matakatsu and Blair, 2012)
Mutagen
in vitro construct
(Matakatsu and Blair, 2012)
Progenitor genotype
Carried in construct
P{UAS-ft.ΔECD.HA}
Cytology
Description

UAS regulatory sequences drive expression of ft lacking most of the extracellular domain (a portion of the first of the 34 cadherin domains remains). The protein is tagged at the C-terminal end with Tag:HA.

(Matakatsu and Blair, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
ft
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ftΔECD.UAS.Tag:HA/Scer\GAL4hh-Gal4 rescues ftunspecified

      (Matakatsu and Blair, 2012)
      Partially rescues

      Scer\GAL4Act.PU/ftΔECD.UAS.Tag:HA partially rescues ft8/ftG-rv

      (Matakatsu and Blair, 2012)
      Comments

      Expression of ftΔECD.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act.PU in ftG-rv/ft8 animals rescues disc overgrowth, allows eclosion and substantially improves hair planar cell polarity defects in the wing and abdomen.

      Expression of ftΔECD.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4hh-Gal4 strongly rescues overgrowth of the posterior compartment of the wing disc in ftunspecified animals.

      (Matakatsu and Blair, 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ftΔECD.Scer\UAS.T:Ivir\HA1
      ftΔECD.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)