FlyBase Allele Report: Dmel\dco[hs.PS]

General Information

Symbol

Dmel\dco^hs.PS

Species

D. melanogaster

Name

heat shock construct of Sekine

FlyBase ID

FBal0264170

Feature type

allele

Associated gene

Dmel\dco

Associated Insertion(s)

Carried in Construct

P{hs-dco.S}

Key Links

Transgenic product class

wild_type

(Sekine et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Sekine et al., 2008)

Mutagen

in vitro construct

(Sekine et al., 2008)

Progenitor genotype

Carried in construct

P{hs-dco.S}

Cytology

Description

A heat shock promoter drives expression of dco.

(Sekine et al., 2008)

Allele components

Component

Use(s)

Encoded product / tool

dco

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor rhythm | temperature conditional, with dco^VIII

(Sekine et al., 2008)

Phenotype Manifest In

Detailed Description

Statement

Reference

No locomotor rhythm defects are seen when flies expressing dco^hs.PS in a dco^VIII mutant background are heat shocked. However when dco^hs.PS is expressed in the absence of heat shock approximately 71% of viable flies are arrhythmic.

(Sekine et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

dco^hs.PS rescues dco^VIII

(Sekine et al., 2008)

Comments

Expression of dco^hs.PS under heat shock conditions rescues the lethality associated with dco^VIII. Lethality is also rescued when heat shock is not applied.

(Sekine et al., 2008)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dco^hs.PS

Name Synonyms

heat shock construct of Sekine

Secondary FlyBase IDs

References (1)

Report Sections

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