FB2024_03 , released June 25, 2024
Allele: Dmel\ebiHMS01390
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General Information
Symbol
Dmel\ebiHMS01390
Species
D. melanogaster
Name
FlyBase ID
FBal0263300
Feature type
allele
Associated gene
Dmel\ebi
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS01390}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
in vitro construct
(Ni et al., 2011.7.19)
Progenitor genotype
Carried in construct
P{TRiP.HMS01390}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS01390
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ebiHMS01390 under the control of Scer\GAL4bbg-C96 results in notching along the adult wing margin and a reduction in wing size, as compared to controls.

      (Nguyen et al., 2016)

      Expression of ebiHMS01390 is early pupal lethal (with the Scer\GAL4Act5C.PI driver), pupal lethal with either Scer\GAL4ey.PH or Scer\GAL4en.PU (same result observed at 18[o]C) and results in small wings with missing veins (with Scer\GAL4nub.PK); no overt adult phenotype is observed with the Scer\GAL4GMR.PF driver.

      (Dietz et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Scer\GAL4bbg-C96, ebiHMS01390 has abnormal size phenotype, suppressible | partially by crb11A22/crb[+]

      (Nguyen et al., 2016)

      Scer\GAL4bbg-C96, ebiHMS01390 has visible phenotype, suppressible | partially by crb11A22/crb[+]

      (Nguyen et al., 2016)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4bbg-C96, ebiHMS01390 has wing phenotype, suppressible | partially by crb11A22/crb[+]

      (Nguyen et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      crb11A22/+ partially rescues the wing notch and reduced wing size seen in flies expressing ebiHMS01390 under the control of Scer\GAL4bbg-C96.

      (Nguyen et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ebiHMS01390
      Name Synonyms
      Secondary FlyBase IDs
        References (4)