FB2024_03 , released June 25, 2024
Allele: Dmel\acj6I.UAS
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General Information
Symbol
Dmel\acj6I.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0262479
Feature type
allele
Associated gene
Dmel\acj6
Associated Insertion(s)
Carried in Construct
P{UAS-acj6.isoI}
Key Links
Transgenic product class
wild_type
(Bai and Carlson, 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bai and Carlson, 2010)
Mutagen
in vitro construct
(Bai and Carlson, 2010)
Progenitor genotype
Carried in construct
P{UAS-acj6.isoI}
Cytology
Description

UASt regulatory sequences drive expression of acj6 sequences that code for splice isoform I, containing exons 1,4 the long form of exon 5, exon 6, 7, the short form of exon 8, and exon 9.

(Bai and Carlson, 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
acj6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of acj6I.Scer\UAS under the control of Scer\GAL4acj6-PG63 in a acj6PG63/Y background is able to induce a fenchone odor response, indicating activation of Or85e.

      (Bai and Carlson, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4acj6-PG63/acj6I.UAS partially rescues acj6PG63

      (Bai and Carlson, 2010)

      Scer\GAL4acj6-PG63/acj6I.UAS partially rescues acj66

      (Bai and Carlson, 2010)
      Comments

      Expression of acj6I.Scer\UAS under the control of Scer\GAL4acj6-PG63 rescues the response of the sensilla pb1A neuron to ethyl acetate, isoamyl acetate, 4-methyl phenol, benzaldehyde and fenchone.

      Expression of acj6I.Scer\UAS under the control of Scer\GAL4acj6-PG63 in a acj6PG63/Y background is able to induce a fenchone odor response, indicating activation of Or85e.

      Expression of acj6I.Scer\UAS under the control of Scer\GAL4acj6-PG63 in a acj6PG63/Y background suppresses the (pb2C, 0) type of sensilla normally found in acj6PG63 mutants.

      Expression of acj6I.Scer\UAS under the control of Scer\GAL4acj6-PG63 in a acj6PG63/Y background gives rise to a number of sensillum types of which the most frequent (43%) contains a novel neuron, pb2F, paired with an unresponsive neuron.

      Expression of acj6I.Scer\UAS under the control of Scer\GAL4acj6-PG63 in a acj6PG63/Y background rescues the pb3 sensilla.

      (Bai and Carlson, 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      acj6I.Scer\UAS
      acj6I.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)