Imprecise excision of the progenitor insertion, resulting in a 1368bp deletion starting 150bp upstream of the ATG codon.
A 1368 bp deletion resulting from the imprecise excision of P{EPgy2}dgrnEY09862 extends from the insertion site into the dgrn gene.
Mutants exhibit significant genome instability in larval neuroblasts (in the absence of ionizing radiation), including aneuploidy, chromosome fusions and changes in the number of satellites.
Embryos from homozygous females arrest after two or three nuclear divisions (88% penetrance). The nuclear envelope can form in these embryos, but it does so around chromosome pieces rather than as a single nucleus. 12% of embryos derived from homozygous females overcome this early arrest phenotype, however, they arrest prior to gastrulation with a phenotype in which nuclei that do reach the surface of the embryo subsequently fall inwards and form a halo just under the surface or aggregate at the centre of the embryo. Most of the nuclei in these late arrest embryos form a single nuclear envelope, but there are distortions in nuclear size and shape.
dgrnDK is an enhancer of visible phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS
dgrn[+]/dgrnDK is a suppressor | maternal effect | partially of lethal | embryonic stage phenotype of hry30/hry26
dgrn[+]/dgrnDK is a suppressor of embryonic/larval segmentation phenotype phenotype of hry26
dgrnDK is an enhancer of eye phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS
dgrnDK/+ suppresses the formation of ectopic wing bristles seen in h1/h26 flies, predominantly within the intervein regions.
The defects in segmentation which are seen in homozygous h26 embryos are partially suppressed by dgrnDK/+; 50% of the double mutant embryos have more than 4 segments.
A maternal copy of dgrnDK/+ partially suppresses the embryonic lethality of the h30/h26 combination; only 19% of the embryos fail to hatch.
