FB2024_03 , released June 25, 2024
Allele: Dmel\tupRNAi.UAS
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General Information
Symbol
Dmel\tupRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0257007
Feature type
allele
Associated gene
Dmel\tup
Associated Insertion(s)
Carried in Construct
P{UAS-tup.RNAi}
Also Known As
UAS-tupIR
Key Links
Transgenic product class
RNAi_reagent
(de Navascués and Modolell, 2007)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(de Navascués and Modolell, 2007)
Mutagen
in vitro construct
(de Navascués and Modolell, 2007)
Progenitor genotype
Carried in construct
P{UAS-tup.RNAi}
Cytology
Description

UAS regulatory sequences drive expression of an 810 nucleotide tup cDNA fragment in an RNAi construct.

(de Navascués and Modolell, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
tup
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of tupdsRNA.Scer\UAS in the notum territory with Scer\GAL4MS248 results in many extra scutellar bristle, although no extra dorsocentral bristles are observed.

      Overexpression of tupdsRNA.Scer\UAS under the control of Scer\GAL4MS248 engenders a decrease in the number of dorsocentral bristles.

      Overexpression of tupdsRNA.Scer\UAS under the control of Scer\GAL4pnr-MD237 results in the formation of up to two supernumerary scutellar bristles per heminotum.

      (de Navascués and Modolell, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Enhancer of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Overexpression of tupdsRNA.Scer\UAS under the control of Scer\GAL4pnr-MD237 in a scase-1 mutant background does not lead to the formation of supernumerary scutellar bristles.

      Overexpression of tupdsRNA.Scer\UAS under the control of Scer\GAL4pnr-MD237 in a scA mutant background does not lead to the formation of supernumerary scutellar bristles.

      Roughly twice as many bristles are generated when both tupdsRNA.Scer\UAS and scScer\UAS.cPa are overexpressed under the control of Scer\GAL4pnr-MD237 in a homozygous scA mutant background compared with that of scScer\UAS.cPa overexpression alone.

      (de Navascués and Modolell, 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tupRNAi.UAS
      tupdsRNA.Scer\UAS
      tupdsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)