FB2024_03 , released June 25, 2024
Allele: Dmel\MadUAS.Tag:MYC
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General Information
Symbol
Dmel\MadUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0256856
Feature type
allele
Associated gene
Dmel\Mad
Associated Insertion(s)
Carried in Construct
P{UAS-Myc-Mad}
Also Known As
UAS-Myc-Mad
Key Links
Transgenic product class
wild_type
(Merino et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Merino et al., 2009)
Mutagen
in vitro construct
(Merino et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-Myc-Mad}
Cytology
Description

UASt regulatory sequences drive expression of the full-length Mad open reading frame, which is tagged at the N-terminal end with 6 copies of Tag:MYC.

(Merino et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mad
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of MadScer\UAS.T:Hsap\MYC under the control of Scer\GAL4BG380 does not significantly alter the number of boutons per muscle surface area at the neuromuscular junction of third instar larvae.

      (Merino et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of MadScer\UAS.T:Hsap\MYC under the control of Scer\GAL4BG380 does not suppress the reduction in the number of boutons per muscle surface area which is seen at the neuromuscular junction in nmounspecified third instar larvae.

      (Merino et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4unspecified/MadUAS.Tag:MYC rescues Madk00237

      (Merino et al., 2009)

      Scer\GAL4BG380/MadUAS.Tag:MYC rescues Madk00237

      (Merino et al., 2009)
      Comments

      Neuronal expression of MadScer\UAS.T:Hsap\MYC under the control of Scer\GAL4unspecified rescues the reduction in the number of boutons per muscle surface area that is seen at the neuromuscular junction in Madk00237 third instar larvae.

      Expression of MadScer\UAS.T:Hsap\MYC under the control of Scer\GAL4BG380 rescues the electrophysiological defects seen at the neuromuscular junction of Madk00237 third instar larvae.

      (Merino et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MadScer\UAS.T:Hsap\MYC
      MadUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (3)