UAS drives expression of the I-467 isoform of Hsap\PSEN1.
The expression of Hsap\PSEN1Scer\UAS.VTR under the control of Scer\GAL4elav-C155 does not lead to any obvious lethality, wing or eye phenotypes, as compared to controls.
Hsap\PSEN1UAS.VTR, Scer\GAL4elav-C155 is a non-suppressor of lethal - all die during pupal stage | male limited phenotype of PsnRNAi.UAS.2, Scer\GAL4elav-C155
Hsap\PSEN1UAS.VTR, Scer\GAL4elav-C155 is a non-suppressor of wing | female limited | adult stage phenotype of PsnRNAi.UAS.2, Scer\GAL4elav-C155
Hsap\PSEN1UAS.VTR, Scer\GAL4elav-C155 is a non-suppressor of eye | female limited | adult stage phenotype of PsnRNAi.UAS.2, Scer\GAL4elav-C155
The co-expression of Hsap\PSEN1Scer\UAS.VTR does not suppress either the pupal lethality in males or the rough eye and wrinkled wing phenotypes in females observed upon the expression of PsndsRNA.shRNA.Scer\UAS.2 under the control of Scer\GAL4elav-C155.