FB2024_03 , released June 25, 2024
Allele: Scer\GAL4GMR84B12
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General Information
Symbol
Scer\GAL4GMR84B12
Species
S. cerevisiae
Name
FlyBase ID
FBal0255480
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR84B12-GAL4}
Also Known As
GscG-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR84B12-GAL4}
Cytology
Description

A 1087 base pair fragment from the flanking non-coding or intronic region of Gsc is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR84B12
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 11
      precursor cell of the stomatogastric nervous system | subset
      (Hernández et al., 2015)
      embryonic stage 11 -- 12
      foregut primordium
      (Hernández et al., 2015)
      embryonic stage 12 -- 13
      embryonic esophagus
      (Hernández et al., 2015)
      embryonic stage 12 -- 17
      delaminating stomatogastric nervous system precursor
      (Hernández et al., 2015)
      embryonic stage 15 -- 17
      embryonic stomatogastric nervous system
      (Hernández et al., 2015)
      larval gnathal ganglion
      (Hernández et al., 2015)
      embryonic head sensory system | restricted
      (Hernández et al., 2015)
      embryonic stage 16 -- 17
      embryonic/larval foregut
      (Hernández et al., 2015)
      embryonic/larval proventriculus
      (Hernández et al., 2015)
      embryonic/larval brain
      (Hernández et al., 2015)
      embryonic stage 17
      embryonic/larval frontal ganglion
      (Hernández et al., 2015)
      embryonic/larval frontal nerve
      (Hernández et al., 2015)
      Additional Information
      Statement
      Reference

      ScerGAL4GMR84B12 drives expression in pre-migrating SNS cells, and in all three SNS clusters from the start of delamination through the end of embryogenesis; all SNS cells are labeled by the end of embryogenesis. Expression is also driven in the developing embryonic foregut starting at embryonic stage 12.

      (Hernández et al., 2015)
       
      Marker for
      Reflects expression of
      Gsc
      (Hernández et al., 2015)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos derived from mothers carrying Scer\GAL4GMR84B12 produce shorter embryos. No effect is seen when fathers carry Scer\GAL4GMR84B12. A large number of the embryos fail to hatch.

      (Hernández et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR84B12
      Name Synonyms
      Secondary FlyBase IDs
        References (3)