FB2024_04 , released June 25, 2024
Allele: Dmel\crolLAJJ2A
Open Close
General Information
Symbol
Dmel\crolLAJJ2A
Species
D. melanogaster
Name
FlyBase ID
FBal0248771
Feature type
allele
Associated gene
Dmel\crol
Associated Insertion(s)
P{Mae-UAS.6.11}crolLAJJ2A
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schneiderman et al., 2010)
Progenitor genotype
Associated Insertion(s)
P{Mae-UAS.6.11}crolLAJJ2A
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{Mae-UAS.6.11}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of crolLAJJ2A driven by Scer\GAL4Act5C.PI results in lethality.

      (Schneiderman et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      crolLAJJ2A/Scer\GAL4ey.PH is a suppressor of eye phenotype of bwD

      (Schneiderman et al., 2010)
      Other
      Statement
      Reference

      Scer\GAL4GMR.PF, bwD, crolLAJJ2A has eye phenotype

      (Schneiderman et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Mis-expression of crolLAJJ2A driven by Scer\GAL4GMR.PF results in increased eye pigmentation in bwD/+ heterozygotes compared with that in the parental bwD/+ line. Flies expressing Scer\GAL4GMR.PF-driven crolLAJJ2A in a bwD/+ genetic background display rough eyes.

      Flies expressing Scer\GAL4ey.PH-driven crolLAJJ2A in a bwD/+ genetic background display sectors of increased pigmentation in a speckled background.

      Mis-expression of crolLAJJ2A driven by Scer\GAL4ey.PH partially suppresses the In(1)wm4-associated eye colour phenotype.

      (Schneiderman et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      crolLAJJ2A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)