UAS regulatory sequences drive expression of an inverted repeat.
Expression of Mmp2JF01337 under the control of Scer\GAL4GMR.PU does not lead to any photoreceptor degeneration and ommatidial disorganization in the adult eye.
Knockdown of Mmp2JF01337 driven by Scer\GAL4Act.PU during adulthood (using Scer\GAL80ts.αTub84B) causes a significant reduction in egg laying compared to wild type.
Expression of Mmp2JF01337 under the control of Scer\GAL4bab1-Pgal4-2 (using the temperature sensitive Scer\GAL80ts.αTub84B allele to limit expression to the adult stage) results in an increase in the average number of cells in the interfollicle stalks compared to wild type.
Scer\GAL4elav.PU, Hsap\CCN2UAS.cYa, Mmp2JF01337 is a non-suppressor of ommatidium | adult stage | progressive phenotype of Hsap\APPAβ42.UAS.cBa, Scer\GAL4GMR.PU
Scer\GAL4elav.PU, Hsap\CCN2UAS.cYa, Mmp2JF01337 is a non-suppressor of rhabdomere | adult stage | progressive phenotype of Hsap\APPAβ42.UAS.cBa, Scer\GAL4GMR.PU
The progressive photoreceptor degeneration in the adult eye observed upon Scer\GAL4GMR.PU-driven expression of Hsap\APPAβ42.Scer\UAS.cBa can be significantly suppressed by co-expression of Hsap\CTGFUAS.cYa but not by co-expression of Hsap\CTGFUAS.cYa combined with Mmp2JF01337.