Expression of sli^JF01229 under the control of Scer\GAL4^elav-C155 (in sli²/+ background), Scer\GAL4^repo (in sli²/+ background) or Scer\GAL4^ey-OK107 (in Df(2R)BSC482/+ background) leads to ectopic inner proliferating center cell clusters in the medulla of third instar larvae (higher penetrance with Scer\GAL4^elav-C155 than Scer\GAL4^repo) when compared to controls.

Expression of sli^JF01229 under the control of Scer\GAL4^elav-C155 (in Df(2R)BSC482/+ background), Scer\GAL4^repo (in Df(2R)BSC482/+ background), Scer\GAL4^ey-OK107 (in Df(2R)BSC482/+ background, in combination with Dicer-2) or Scer\GAL4^ap-md544 (in Df(2R)BSC482/+ background, in combination with -Dicer-2) leads to defects in the adult optic lobes (higher penetrance with Scer\GAL4^ey-OK107 than Scer\GAL4^ap-md544) when compared to controls.

In detail: expression of sli^JF01229 under the control of Scer\GAL4^elav-C155 (in Df(2R)BSC482/+ background) or Scer\GAL4^ey-OK107 (in Df(2R)BSC482/+ background, in combination with Dicer-2) but not Scer\GAL4^repo (inDf(2R)BSC482/+ background) or Scer\GAL4^GMR.PU (in Df(2R)BSC482/+ background) leads to elongated optic lobes with either defects in the organization of the cell bodies (with Scer\GAL4^elav-C155 in Df(2R)BSC482/+ background) or disturbed innervation patterns of photoreceptor cells (with Scer\GAL4^ey-OK107 (in Df(2R)BSC482/+ background, in combination with Dicer-2); its expression under the control of Scer\GAL4^repo (in Df(2R)BSC482/+ background) leads to defects in the optic lobe organization and a decrease in the ratio between the distal medulla cortex and optic lobe areas; and its expression under the control of Scer\GAL4^GMR.PU (in Df(2R)BSC482/+ background) or Scer\GAL4^repo (in Df(2R)BSC482/+ background) leads to defects in the medulla (specifically sporadic gaps with Scer\GAL4^GMR.PU) and disturbed innervation patterns of photoreceptor cells when compared to control adults.

The expression of sli^JF01229 under the control of Scer\GAL4^pros-V1 leads to a significant increase in the number of pre-enteroendocrine cells, as compared to controls.

The adult sLNv neurons of sli² heterozygotes that also express sli^JF01229 under the control of Scer\GAL4^ey-OK107 (in combination with Dicer-2, for efficient RNAi) exhibit significantly longer axon projections compared to controls.

Scer\GAL4^repo.PU/sli^JF01229 is a suppressor | partially of lethal - all die during P-stage phenotype of Scer\GAL4^repo.PU, brm^GD4507

Scer\GAL4^repo.PU/sli^JF01229 is a suppressor | partially of lethal - all die during P-stage phenotype of Scer\GAL4^repo.PU, Snr1^KK101602

Df(2R)BSC482, Scer\GAL4^GMR.PU, sli^JF01229 has abnormal neuroanatomy | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^elav-C155, sli^JF01229 has abnormal neuroanatomy | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^ey-OK107, sli^JF01229 has abnormal neuroanatomy | third instar larval stage phenotype

Df(2R)BSC482, Scer\GAL4^ey-OK107, sli^JF01229 has abnormal neuroanatomy | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^ap-md544, sli^JF01229 has abnormal neuroanatomy | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^repo, sli^JF01229 has abnormal neuroanatomy | adult stage phenotype

Scer\GAL4^repo.PU, brm^GD4507, sli^JF01229 has partially lethal - majority die phenotype

Scer\GAL4^repo.PU, Snr1^KK101602, sli^JF01229 has partially lethal - majority die phenotype

Df(2R)BSC482, Scer\GAL4^ey-OK107, sli^JF01229 has adult optic lobe phenotype

Df(2R)BSC482, Scer\GAL4^repo, sli^JF01229 has eye photoreceptor cell | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^repo, sli^JF01229 has neuron projection | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^GMR.PU, sli^JF01229 has medulla | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^GMR.PU, sli^JF01229 has eye photoreceptor cell | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^GMR.PU, sli^JF01229 has neuron projection | adult stage phenotype

Df(2R)BSC482, Scer\GAL4^elav-C155, sli^JF01229 has adult optic lobe phenotype

Df(2R)BSC482, Scer\GAL4^ey-OK107, sli^JF01229 has larval inner optic anlage | ectopic | third instar larval stage phenotype

Df(2R)BSC482, Scer\GAL4^ap-md544, sli^JF01229 has adult optic lobe phenotype

Df(2R)BSC482, Scer\GAL4^repo, sli^JF01229 has adult optic lobe phenotype

Df(2R)BSC482, Scer\GAL4^repo, sli^JF01229 has medulla | adult stage phenotype