FB2024_03 , released June 25, 2024
Allele: Dmel\dlp-HS.UAS
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General Information
Symbol
Dmel\dlp-HS.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0244464
Feature type
allele
Associated gene
Dmel\dlp
Associated Insertion(s)
Carried in Construct
P{UAS-dlp.-HS}
Also Known As
UAS-dlp(-HS)
Key Links
Transgenic product class
inframe_deletion
(Yan et al., 2009)
missense_variant
(Yan et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Yan et al., 2009)
missense_variant
(Yan et al., 2009)
Mutagen
in vitro construct
(Yan et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-dlp.-HS}
Cytology
Description

UASt regulatory sequences drive expression of a mutated form of dlp in which all five potential GAG attachment sites (Ser625, Ser629, Ser631, Ser643 and Ser686) have been converted to Ala.

(Yan et al., 2009)

UAS regulatory sequences drive expression of a mutated form of dlp in which all of the GAG attachment sites have been mutated and also the GPI anchor has been replaced by the T:Rnor\CD2 transmembrane protein. A EGFP tag has been inserted at a unique NdeI site.

(Yan et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
UASt
Encoded product / tool
dlp
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The ability of dlp-HS.Scer\UAS expressed under the control of Scer\GAL4prd.RG1 to rescue naked cuticle patterning in dlpA187 embryos derived from dlpA187 female germline clones is not affected if the embryos are also mutant for dally80.

      (Yan et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4prd.RG1/dlp-HS.UAS rescues dlpA187

      (Yan et al., 2010)
      Comments

      Expression of dlp-HS.Scer\UAS under the control of Scer\GAL4prd.RG1 effectively rescues naked cuticle patterning cell-autonomously in dlpA187 embryos derived from dlpA187 female germline clones.

      (Yan et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dlp-HS.Scer\UAS
      dlp-HS.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)