FB2024_03 , released June 25, 2024
Allele: Dmel\KrnRNAi.UAS
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General Information
Symbol
Dmel\KrnRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0244006
Feature type
allele
Associated gene
Dmel\Krn
Associated Insertion(s)
Carried in Construct
P{UAS-krn.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Brown et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Brown et al., 2007)
Mutagen
in vitro construct
(Brown et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-krn.RNAi}
Cytology
Description

UAS drives expression of a RNAi construct of Krn comprising 600 bp of the Krn coding region.

(Brown et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Krn
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing KrndsRNA.Scer\UAS under the control of Scer\GAL4GMR.PF are phenotypically wild type.

      (Brown et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      KrnRNAi.UAS/Scer\GAL4GMR.PF is an enhancer of eye phenotype of S05671

      (Brown et al., 2007)

      KrnRNAi.UAS/Scer\GAL4GMR.PF is an enhancer of ommatidium phenotype of S05671

      (Brown et al., 2007)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4GMR.PF-driven expression of KrndsRNA.Scer\UAS enhances the S05671/+ eye phenotype. Both ommatidial rotation and recruitment defects are observed. Around 2% of ommatidia have too many photoreceptors. Occasional achiral ommatidia are observed.

      (Brown et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      KrnRNAi.UAS/Scer\GAL4GMR.PF rescues KrnUAS.cUa

      (Brown et al., 2007)
      Comments

      Expression of KrndsRNA.Scer\UASsuppresses the rough eye and ectopic wing venation phenotypes seen in KrnScer\UAS.cUa, Scer\GAL4GMR.PF flies.

      (Brown et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      KrnRNAi.UAS
      KrndsRNA.Scer\UAS
      KrndsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)