FB2024_03 , released June 25, 2024
Allele: Dmel\paraJS1-Ex8
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General Information
Symbol
Dmel\paraJS1-Ex8
Species
D. melanogaster
Name
FlyBase ID
FBal0243140
Feature type
allele
Associated gene
Dmel\para
Associated Insertion(s)
P{?lacW}paraJS1-Ex8
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Song and Tanouye, 2007)
Progenitor genotype
paraJS1
(Song and Tanouye, 2007)
Associated Insertion(s)
P{?lacW}paraJS1-Ex8
Cytology
Description

Imprecise excision of P{lacW}paraJS1 has deleted only a small part of the insert. remaining.

(Song and Tanouye, 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      para[+]/paraJS1-Ex8 is a suppressor of bang sensitive | recessive phenotype of eas2

      (Song and Tanouye, 2007)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      paraJS1-Ex8 dominantly suppresses the bang sensitive phenotype of eas2 homozygotes to a similar degree to as paraJS1. The minimum voltage of high frequency stimulation of the brain required to induce seizure (the seizure threshold) of eas2 homozygotes is raised to almost wild-type levels by paraJS1-Ex8/+.

      (Song and Tanouye, 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      paraJS1-Ex8
      paraJS1 Ex8
      (Song and Tanouye, 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)