Insertion at the beginning of the exon that is specific to the Ank2 XL isoform. This results in the addition of 60 amino acids encoded by Dhyd\Minos sequence after V2666 and a premature stop codon.
Ank2MB04517/Ank2MB04517 mutant larval neuromuscular junctions exhibit a dramatic perturbation of presynaptic microtubule cytoskeleton organization, as compared to controls, but these mutants do not exhibit a significant increase in synaptic retraction frequency.