FB2024_03 , released June 25, 2024
Allele: Dmel\TBPHHM05194
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General Information
Symbol
Dmel\TBPHHM05194
Species
D. melanogaster
Name
FlyBase ID
FBal0242113
Feature type
allele
Associated gene
Dmel\TBPH
Associated Insertion(s)
Carried in Construct
P{TRiP.HM05194}
Also Known As
TBPH RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.HM05194}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HM05194
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  amyotrophic lateral sclerosis type 10
      CEA
      (Jantrapirom et al., 2018)
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Depending on the driver line insertion, the expression of TBPHKK108354 under the control of Scer\GAL4GMR.PS results in a rough eye morphology. The expression under the control of Scer\GAL4elav.PLu effected the locomotive abilities of L3 larvae, but not of adults.

      (Jantrapirom et al., 2018)

      Expression of TBPHHM05194 in the fat body under the control of Scer\GAL4DcG results in significant hyperglycaemia.

      (Ugrankar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4GMR.PS, TBPHHM05194 has eye phenotype, enhanceable by Scer\GAL4GMR.PS/UbqnKK100857

      (Jantrapirom et al., 2018)
      Enhancer of
      Statement
      Reference

      TBPHHM05194/Scer\GAL4GMR.PS is an enhancer of eye phenotype of Scer\GAL4GMR.PS, UbqnKK100857

      (Jantrapirom et al., 2018)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      TBPHHM05194
      Name Synonyms
      Secondary FlyBase IDs
        References (7)