FB2024_03 , released June 25, 2024
Allele: Dmel\NΔEGF1-36.LV.UAS
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General Information
Symbol
Dmel\NΔEGF1-36.LV.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0241579
Feature type
allele
Associated gene
Dmel\N
Associated Insertion(s)
Carried in Construct
P{UAS-N.ΔEGF.LV}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Loewer et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-N.ΔEGF.LV}
Cytology
Description

UAS regulatory sequences drive expression of N lacking the 36 EGF repeats and fused to a nuclear localization signal (Tag:NLS(SV40-largeT)) followed by sequence encoding a lexA::VP16 driver at its C-terminal end.

(Loewer et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
N
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      NΔEGF1-36.LV.UAS/Scer\GAL4hh-Gal4 is an enhancer of phenotype of l(2)gd1d7

      (Schneider et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4hh-Gal4-mediated expression of NΔEGF1-36.Scer\UAS.T:Hsim\VP16,T:Ecol\lexA enhances the ectopic N activation phenotype (ectopic expression of wg) in the posterior of l(2)gd1d7 wing discs.

      (Schneider et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      NΔEGF1-36.LV.UAS
      NΔEGF1-36.Scer\UAS.T:Hsim\VP16,T:Ecol\lexA
      NΔEGF1-36.Scer\UAS.T:Hsim\VP16.T:Ecol\lexA
      Name Synonyms
      Secondary FlyBase IDs
        References (4)