FB2024_03 , released June 25, 2024
Allele: Dmel\salsUAS.cBa
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General Information
Symbol
Dmel\salsUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Bai
FlyBase ID
FBal0239922
Feature type
allele
Associated gene
Dmel\sals
Associated Insertion(s)
Carried in Construct
P{UAS-sals.B}
Key Links
Transgenic product class
wild_type
(Bai et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bai et al., 2007)
Mutagen
in vitro construct
(Bai et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-sals.B}
Cytology
Description

UAS regulatory sequences drive expression of the long form of sals.

(Bai et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
sals
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      65% of embryos expressing salsScer\UAS.cBa under the control of Scer\GAL4Mef2.PR fail to hatch at 29[o]C. The remaining embryos hatch, but crawl very slowly and later died.

      Approximately 90% of primary muscle cells isolated from embryos expressing salsScer\UAS.cBa under the control of Scer\GAL4Mef2.PR have completely lost the striated pattern of thin and thick filaments when examined after culture for 5 days at 29[o]C . Approximately 7% of primary muscle cells isolated from embryos expressing salsScer\UAS.cBa under the control of Scer\GAL4Mef2.PR have myofibrils with an aberrant striated pattern with longer than usual sarcomeres.

      (Bai et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      salsUAS.cBa/Scer\GAL4Mef2.PR rescues salsf07849

      (Bai et al., 2007)
      Comments

      Expression of salsScer\UAS.cBa under the control of Scer\GAL4Mef2.PR rescues the myofibril defects seen in primary muscle cultures derived from myoblasts dissociated from salsf07849 mutant embryos

      (Bai et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      salsScer\UAS.cBa
      salsUAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Bai
      Secondary FlyBase IDs
        References (1)