abnormal neuroanatomy | embryonic stage | maternal effect (with Df(3R)JY19), with AbiP2
larval longitudinal connective | maternal effect (with Df(3R)JY19), with AbiP2
More than 60% of AbiP1/Df(3R)JY19 and AbiP1/AbiKO animals survive to adulthood.
Embryos maternally hypomorphic for Abi function and lacking zygotic Abi function (derived from AbiP1/Df(3R)JY19 females mated to AbiP2 carrying males) have deranged longitudinal connectives and commissural tracts. 57.1% of these embryos have midline crossing defects in ipsilateral axon fascicles at stage 17.