FB2024_04 , released June 25, 2024
Allele: Dmel\Chd1EP
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General Information
Symbol
Dmel\Chd1EP
Species
D. melanogaster
Name
FlyBase ID
FBal0239119
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description

    Insertion at nucleotide position -2 relative to the transcription start site.

    Allele components
    Component
    Use(s)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Expression of Chd1EP driven by Scer\GAL4Act5C.PI results in lethality in males.

    Expression of Chd1EP under the control of Scer\GAL4GMR.PF reduces the eye pigmentation in Dp(?;2)bwD/bw[+] animals.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhancer of
    Statement
    Reference
    Phenotype Manifest In
    Enhancer of
    Statement
    Reference

    Chd1EP/Scer\GAL4GMR.PF is an enhancer of eye phenotype of bwD

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Mis-expression of Chd1EP driven by Scer\GAL4GMR.PF results in decreased eye pigmentation in bwD/+ heterozygotes compared with that in the parental bwD/+ line.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (2)