FlyBase Allele Report: Dmel\hng3[KK111648]

General Information

Symbol

Dmel\hng3^KK111648

Species

D. melanogaster

Name

FlyBase ID

FBal0237565

Feature type

allele

Associated gene

Dmel\hng3

Associated Insertion(s)

Carried in Construct

P{KK111648}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK111648}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK111648

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

flightless, with Scer\GAL4^Bx-MS1096

(Shukla et al., 2014)

visible, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Phenotype Manifest In

wing, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

wing hinge, with Scer\GAL4^Bx-MS1096

(Shukla et al., 2014)

Detailed Description

Statement

Reference

Expression of hng3^KK111648 under the control of Scer\GAL4^Bx-MS1096 results in male flies with severe wing size and patterning defects.

Expression of hng3^KK111648 under the control of Scer\GAL4^Bx-MS1096 results in female flies with weak wing size and patterning defects.

(Schertel et al., 2015)

Expression of hng3^KK111648 under the control of Scer\GAL4^Bx-MS1096 leads to wing hinge defects in the adult fly.

(Shukla et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

hng3^KK111648/Scer\GAL4^Bx-MS1096 is an enhancer of visible phenotype of Scer\GAL4^Bx-MS1096, hng1^KK103642

(Shukla et al., 2014)

hng3^KK111648/Scer\GAL4^Bx-MS1096 is an enhancer of abnormal size phenotype of Scer\GAL4^Bx-MS1096, hng1^KK103642

(Shukla et al., 2014)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, hng3^KK111648 has wing hinge phenotype, non-suppressible by hng1^UASp.cSa/Scer\GAL4^Bx-MS1096

(Shukla et al., 2014)

Enhancer of

Statement

Reference

hng3^KK111648/Scer\GAL4^Bx-MS1096 is an enhancer of wing phenotype of Scer\GAL4^Bx-MS1096, hng1^KK103642

(Shukla et al., 2014)

hng3^KK111648/Scer\GAL4^Bx-MS1096 is an enhancer of alula phenotype of Scer\GAL4^Bx-MS1096, hng1^KK103642

(Shukla et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of hng3^KK111648 enhances the wing hinge phenotype seen when hng1^KK103642 is expressed under the control of Scer\GAL4^Bx-MS1096.

Expression of hng1^{Scer\UAS.P\T.cSa} does not rescue the wing hinge defects seen when hng3^KK111648 is expressed under the control of Scer\GAL4^Bx-MS1096.

(Shukla et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v108487

P{KK111648}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG13897^KK111648

hng3^KK111648

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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