UASt regulatory sequences drive expression of an inverted repeat.
Expression of smKK108588 under the control of Scer\GAL4GMR.PU has no obvious effect on adult eye morphology, whereas expression driven by Scer\GAL4elav.PU results in significant decrease in adult climbing ability.
Scer\GAL4elav.PU, smKK108588 has abnormal locomotor behavior | adult stage phenotype, enhanceable by TBPHRNAi.UAS.cUa/Scer\GAL4elav.PU/TBPH[+]/TBPHΔ23
smKK108588/Scer\GAL4elav.PU is an enhancer of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4elav.PU, TBPHΔ23, TBPHRNAi.UAS.cUa
smKK108588/Scer\GAL4GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4GMR.PU, TBPHUAS.Tag:FLAG
smKK108588/Scer\GAL4GMR.PU is a suppressor | partially of melanotic mass phenotype | adult stage phenotype of Scer\GAL4GMR.PU, TBPHUAS.Tag:FLAG
smKK108588/Scer\GAL4GMR.PU is a suppressor | partially of abnormal eye color phenotype of Scer\GAL4GMR.PU, TBPHUAS.Tag:FLAG
smKK108588/Scer\GAL4GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4GMR.PU, TBPHUAS.Tag:FLAG
smKK108588/Scer\GAL4GMR.PU is a suppressor | partially of ommatidium | adult stage phenotype of Scer\GAL4GMR.PU, TBPHUAS.Tag:FLAG
The climbing ability deficit observed both in the TBPH hypomorphic flies (TBPHΔ23/+;Scer\GAL4elav.PU>TBPHdsRNA.Scer\UAS.cUa, UAS-Dicer2) and flies expressing smKK108588 (also with UAS-Dicer2 and under Scer\GAL4elav.PU control) is much enhanced when the two mutants are combined.
The eye degeneration phenotype (appearance of melanotic spots, fusion of ommatidia) characteristic for adult flies expressing TBPHScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PU is mildly suppressed by co-expression of smKK108588.