FlyBase Allele Report: Dmel\Vmat[Δ14]

General Information

Symbol

Dmel\Vmat^Δ14

Species

D. melanogaster

Name

FlyBase ID

FBal0220991

Feature type

allele

Associated gene

Dmel\Vmat

Associated Insertion(s)

P{?lacW}Vmat^Δ14

Carried in Construct

Key Links

Allele class

hypomorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - molecular evidence

(Romero-Calderón et al., 2008)

Mutagen

P-element activity

(Simon et al., 2009)

Delta2-3 transposase

(Romero-Calderón et al., 2008)

Progenitor genotype

Vmat^SH0459

(Simon et al., 2009, Romero-Calderón et al., 2008)

Associated Insertion(s)

P{?lacW}Vmat^Δ14

Cytology

Description

Imprecise excision of the P-element from Vmat^SH0459. Most of the transposon is removed including the white w eye marker. 51 base pairs in the 6th and last coding exons remain.

(Romero-Calderón et al., 2008)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile

(Simon et al., 2009)

female sterile (with Df(2R)CX1)

(Simon et al., 2009)

lethal (with Df(2R)CX1)

(Simon et al., 2009)

lethal | recessive

(Simon et al., 2009)

male sterile

(Simon et al., 2009)

male sterile (with Df(2R)CX1)

(Simon et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Under standard culture conditions, less than 1% of homozygotes survive to adulthood, but if the density of the cultures is reduced, more homozygotes eclose and survive to adulthood.

Homozygous females can give rise to a few adult progeny. Only 24% of homozygous males produce adult progeny when mated with wild-type females.

(Simon et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

VMAT^Δ14

(Wang et al., 2011)

Vmat^Δ14

(Romero-Calderón et al., 2008)

dVMAT^Δ14

(Simon et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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