FB2024_03 , released June 25, 2024
Allele: Dmel\Pabp2I61S.g
Open Close
General Information
Symbol
Dmel\Pabp2I61S.g
Species
D. melanogaster
Name
FlyBase ID
FBal0219385
Feature type
allele
Associated gene
Dmel\Pabp2
Associated Insertion(s)
Carried in Construct
P{Pabp2.I61S}
Key Links
Transgenic product class
missense_variant
(Benoit et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Benoit et al., 2005)
Mutagen
in vitro construct
(Benoit et al., 2005)
Progenitor genotype
Pabp2+t.g
(Benoit et al., 2005)
Carried in construct
P{Pabp2.I61S}
Cytology
Description

Amino acid replacement: I61S.

(Benoit et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
Pabp2
Encoded product / tool
Pabp2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Pabp2I61S.g partially rescues Pabp2EP2264

      (Benoit et al., 2005)

      Pabp2I61S.g partially rescues Pabp26

      (Benoit et al., 2005)
      Fails to rescue

      Pabp2I61S.g fails to rescue Pabp255/Df(2R)CA53

      (Benoit et al., 2005)
      Comments

      Pabp2I61S.g/+ fails to rescue the lethality due to Pabp255/Df(2R)CA53, weakly rescues lethality due to Pabp2EP2264/Pabp2EP2264 (only 4% escapers) and partially rescues lethality due to Pabp26/Pabp26. The maternal effect embryonic lethality due to Pabp26 is rescued when the mothers also carry Pabp2I61S.g.

      (Benoit et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Pabp2I61S.g
      Name Synonyms
      Secondary FlyBase IDs
        References (1)