Amino acid replacement: E87K.
Amino acid replacement: H90G.
Expression of Fer1HCHmut.Scer\UAS alone under the control of Scer\GAL4Act does not result in increased resistance to paraquat compared to control flies.
Fer1HCHmut.UAS, Scer\GAL4ninaE.PT, Fer2LCHUAS.cMa is a non-suppressor of abnormal neurophysiology | somatic clone | adult stage phenotype of fh1
Scer\GAL4Act.PU/Fer1HCHmut.UAS is a non-suppressor of lethal | recessive phenotype of Fer2LCH00035
Fer1HCHmut.UAS, Scer\GAL4ninaE.PT, Fer2LCHUAS.cMa is a non-suppressor of eye photoreceptor cell | somatic clone | adult stage phenotype of fh1
Expression of both Fer1HCHmut.Scer\UAS and Fer2LCHScer\UAS.cMa under the control of Scer\GAL4ninaE.PT fails to rescue the neurodegeneration and electrophysiology defect seen in fh1 mutant photoreceptor clones when flies are raised in the dark.
Co-expression of both Fer1HCHmut.Scer\UAS and Fer2LCHScer\UAS.cMa under the control of Scer\GAL4Act results in females with greater resistance to paraquat than wild-type controls (males show the same sensitivity to paraquat as controls).
Scer\GAL4Act.PU/Fer1HCHmut.UAS fails to rescue Fer1HCH00451
Scer\GAL4Act.PU/Fer1HCHmut.UAS fails to rescue Fer1HCHG00188/Fer1HCH00451