FB2024_03 , released June 25, 2024
Allele: Dmel\UbqnRNAi.CDS.UAS
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General Information
Symbol
Dmel\UbqnRNAi.CDS.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0217492
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a miRNA targeted to the Ubqn coding region.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of UbqnmiRNA.CDS.Scer\UAS under the control of Scer\GAL4Bx-MS1096 results in multiple wing phenotypes, including crumpled wings, severely shortened wing veins L3-L5 and missing crossveins.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Suppressed by
Statement
Reference
Suppressor of
Phenotype Manifest In
Enhanced by
Suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Heterozygosity for PsnC1 strongly suppresses the wing defects caused by expression of UbqnmiRNA.CDS.Scer\UAS under the control of Scer\GAL4Bx-MS1096.

Co-expression of Psn+14.Scer\UAS strongly enhances the wing defects caused by expression of UbqnmiRNA.CDS.Scer\UAS under the control of Scer\GAL4Bx-MS1096.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Used to study the phenotypic consequences of RNA interference (RNAi) of the Ubqn gene.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
UbqnRNAi.CDS.UAS
UbqnmiRNA.CDS.Scer\UAS
UbqnmiRNA.CDS.UAS
Name Synonyms
Secondary FlyBase IDs
    References (4)