FB2024_03 , released June 25, 2024
Allele: Dmel\Sar111-3-63
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General Information
Symbol
Dmel\Sar111-3-63
Species
D. melanogaster
Name
FlyBase ID
FBal0215582
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
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    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
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    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
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    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In

    dendrite & dendritic arborising neuron

    dendrite & dendritic arborising neuron | somatic clone | cell autonomous

    dendrite & dorsal multidendritic neuron ddaC | somatic clone | cell autonomous

    Golgi apparatus & dendritic arborising neuron | somatic clone | cell autonomous

    Detailed Description
    Statement
    Reference

    Yip1d11-21 mutant ddaC neuron clones show severely simplified dendrite arbors with fewer dendritic termini in white pre-pupae and show strong pruning defects in pupae (16h APF).

    Mutants have reduced dendritic arbors but normal axonal growth in the class IV dendritic arborization (da) neurons.

    Homozygous class IV da neuron single cell clones have reduced dendritic arbors; the total dendritic length in mutant ddaC neuron clones is only 14.9% that of controls. Axonal growth appears normal in these single cell clones, apart from subtle changes at the terminals (the short fibres which resemble filopodia are often missing). The discrete Golgi structures that are normally found in the soma of these cells and the discrete Golgi outposts normally seen in the dendrites are replaced by diffuse structures (as assayed by staining with a Golgi marker).

    External Data
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    Complementation and Rescue Data
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    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
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    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
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    Secondary FlyBase IDs
      References (7)