FB2024_03 , released June 25, 2024
Allele: Mmus\Plpp1UAS.GFP
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General Information
Symbol
Mmus\Plpp1UAS.GFP
Species
M. musculus
Name
FlyBase ID
FBal0212957
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of Mmus\Plpp1 tagged at the C-terminal end with GFP.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos expressing Mmus\Ppap2aScer\UAS.T:Avic\GFP under the control of Scer\GAL4twi.PG show no apparent perturbation or loss of primordial germ cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

The germ cell death seen in embryos with a wun2+ soma which are derived from wun2EP2650ex34/Df(2R)wun-GL females is not rescued by expression of Mmus\Ppap2aScer\UAS.T:Avic\GFP under the control of Scer\GAL4nos.UTR.T:Hsim\VP16.

Expression of Mmus\Ppap2aScer\UAS.T:Avic\GFP under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 in the germ cells does not suppress the reduction in germ cell number seen in embryos expressing wun2αTub84B.T:Hsap\MYC in the soma.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Carried in plasmid "Mouse Lpp1-GFP", transfected into S2 cells and used to study the catalytic activity of the protein produced.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Mmus\Plpp1Scer\UAS.T:Avic\GFP
Mmus\Plpp1UAS.GFP
Mmus\Ppap2aScer\UAS.T:Avic\GFP
Name Synonyms
Secondary FlyBase IDs
    References (3)