Amino acid replacement: G92D.
The lethal phenotype of mod(mdg4)324 is fully complemented by mod(mdg4)Z3-3401, but mod(mdg4)324 fails to complement mod(mdg4)Z3-3401 with respect to X-Y chromosome nondisjunction in male meiosis - transheterozygotes show a high level of X-Y nondisjunction (44.4%).
The lethal phenotype of mod(mdg4)324 is fully complemented by mod(mdg4)Z3-5578 and mod(mdg4)Z3-3298, and mod(mdg4)324 partially or fully complements these alleles with respect to X-Y chromosome nondisjunction in male meiosis - the transheterozygotes show only a low level of X-Y nondisjunction (frequency is indicated in parentheses after each allele); mod(mdg4)Z3-5578 (2.84%) and mod(mdg4)Z3-3298 (5.06%).