UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing x16GD6898 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of x16GD6898 in the developing eye under the control of Scer\GAL4GMR.PF does not affect eye development.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in a weak flyer phenotype.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 0% or 20-30% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 0% or 10-20% of the Scer\GAL4pnr-MD237-expressing area of the notum, depending on the insertion line used.
x16GD6898/Scer\GAL4GMR.PF is a suppressor of increased cell death phenotype of Scer\GAL4GMR.PF, TER94R152H.UAS.R
x16GD6898/Scer\GAL4GMR.PF is a suppressor of eye phenotype of Scer\GAL4GMR.PF, TER94R152H.UAS.R
x16GD6898/Scer\GAL4GMR.PF is a suppressor of ommatidium phenotype of Scer\GAL4GMR.PF, TER94R152H.UAS.R
Expression of x16GD6898 in the developing eye dominantly suppresses the eye degeneration phenotype found upon expression of TER94R152H.Scer\UAS.R (with both transgenes driven by Scer\GAL4GMR.PF). This is concurrent with a significant reduction in the blinded phenotypic severity score.