UASt regulatory sequences drive expression of an inverted repeat.
Expression of esgGD1437 under the control of Scer\GAL4Dl-05151-G leads to abnormal clusters of cells containing enteroendocrine cells, and an overall increase in enteroendocrine cells in the midgut, as compared to controls.
Expression of esgGD1437 under the control of Scer\GAL4Su(H).GBE leads to a reduction in the number of enteroblasts in the adult midgut, but no significant difference in the number of enteroendocrine cells, as compared to controls.
Expression of esgGD1437 in inner proliferation center (IPC) cells under the control of Scer\GAL4Fas3-NP1233 results in ectopic cell clusters adjacent to a continuous with the proximal IPC (p-IPC) neuroepithelium in ~50% of optic lobes. The number of cells stream emerging from the p-IPC is reduced from 4 to 3,2 or 1.
Expression of esgGD1437 under the control of Scer\GAL4Bx-MS1096 results in male flies with weak wing size and patterning defects.
Expression of esgGD1437 under the control of Scer\GAL4Bx-MS1096 has no effect on female wing size or patterning.
Adults expressing esgGD1437 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of esgGD1437 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or partial lethality, depending on the particular P{GD1437} insertion line used.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in flightless flies or late pupal lethality.
Expression under the control of Scer\GAL4Mef2.PR results in grossly normal adult indirect flight muscles.
Expression under the control of Scer\GAL4Mef2.PR results in morphologically wild-type myofibrils in the adult indirect flight muscles.
Expression under the control of Scer\GAL4Mef2.PR results in wild-type sarcomeres in the adult indirect flight muscles.
Expression under the control of Scer\GAL4pnr-MD237 results in lethality or semi-lethality at the pupal stage, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in extra bristles on the notum in 20-30% of the Scer\GAL4pnr-MD237 expression domain.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 30-40% of the Scer\GAL4pnr-MD237-expressing area of the notum.