UASt regulatory sequences drive expression of an inverted repeat.
24 hours after UV-induced nociceptive sensitization, early third instar larvae with expression of dispGD2813 driven by Scer\GAL4ppk.1.9 show significant reduction of thermal allodynia (withdrawal responses to a sub-threshold 38[o]C probe) compared to controls.
Adults expressing dispGD2813 under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver show significantly reduced survival on day 6 after a shift to 29[o]C compared to control flies.
Adults expressing dispGD2813 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Scer\GAL4hh-Gal4/dispGD2813 is a suppressor | partially of increased size | larval stage phenotype of Scer\GAL4hh-Gal4, hhUAS.cIa
dispGD2813/Scer\GAL4ppk.1.9 is a suppressor | partially of abnormal pain response | early third instar larval stage | heat sensitive phenotype of Scer\GAL4ppk.1.9, TkR99DUAS.EGFP
dispGD2813/Scer\GAL4ppk.1.9 is a suppressor | partially of abnormal pain response | early third instar larval stage | heat sensitive phenotype of Scer\GAL4ppk.1.9, hhUAS.cUa
dispGD2813/Scer\GAL4ppk.1.9 is a non-suppressor of abnormal pain response | early third instar larval stage | heat sensitive phenotype of Scer\GAL4ppk.1.9, ptc1130X.UAS
Scer\GAL4hh-Gal4/dispGD2813 is a suppressor | partially of wing disc anterior compartment | larval stage phenotype of Scer\GAL4hh-Gal4, hhUAS.cIa
Co-expression of dispGD2813 significantly suppresses the withdrawal responses to a 38[o]C probe (without pre-exposure to UV) seen in early third instar larvae with hhScer\UAS.cUa or TkR99DScer\UAS.T:Avic\GFP-EGFP over-expressed by Scer\GAL4ppk.1.9 (but no suppression in larvae with ptc1130X.Scer\UAS driven by Scer\GAL4ppk.1.9).