UASt regulatory sequences drive expression of an inverted repeat.
Expression of Tap42GD8900 under the control of Scer\GAL4Act5C.PI causes complete lethality.
Expression of Tap42GD8900 under the control of Scer\GAL4GMR.long does not lead to any apparent defect in the compound eye.
Expression of Tap42GD8900 under the control of Scer\GAL4dpp.blk1 does not lead to any apparent phenotype.
Expression of Tap42GD8900 under the control of Scer\GAL4pnr-MD237 results in reduced survival rate to adulthood, and survivors display a marked thorax cleft, but no wing defects, as compared to controls.
Expression of Tap42GD8900 under the control of Scer\GAL4ap-md544 results in reduced survival rate to adulthood, and survivors display varying degrees of a cleft thorax, completely shrivelled wings, and a subset of these flies display necrosis of the front leg joints, as compared to controls. The wing discs of flies expressing Tap42GD8900 under the control of Scer\GAL4ap-md544 show arrest of cell proliferation in the notum region, but no obvious changes in cell proliferation in the wing compartment; and also show increased apoptosis in the wing blade region, as compared to control wing discs.
Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.
Expression under the control of Scer\GAL41407 results in extreme defects in the shape of ganglion mother cells in the larval brain.
Expression under the control of Scer\GAL41407 results in extreme defects in the shape of neuroblasts in the larval brain.
Expression under the control of Scer\GAL4Mef2.PR results in late pupal lethality.
Scer\GAL4ap-md544, Tap42GD8900 has visible phenotype, suppressible | partially by mtsXE-2258/mts[+]
Scer\GAL4ap-md544, Tap42GD8900 has partially lethal - majority die phenotype, suppressible by mtsXE-2258/mts[+]
Scer\GAL4ap-md544, Tap42GD8900 has visible phenotype, non-suppressible by Scer\GAL4ap-md544/bskDN.UAS.cUa
Scer\GAL4ap-md544, Tap42GD8900 has adult thorax phenotype, suppressible | partially by mtsXE-2258/mts[+]
Scer\GAL4ap-md544, Tap42GD8900 has wing | adult stage phenotype, suppressible | partially by mtsXE-2258/mts[+]
Scer\GAL4ap-md544, Tap42GD8900 has adult thorax phenotype, non-suppressible by Scer\GAL4ap-md544/bskDN.UAS.cUa
Co-expression of bskDN.Scer\UAS.cUa fails to rescue the cleft thorax phenotype of flies expressing Tap42GD8900 under the control of Scer\GAL4ap-md544.
mtsXE-2258/+ partially rescues the cleft thorax and wing phenotypes, and rescues survival of flies expressing Tap42GD8900 under the control of Scer\GAL4ap-md544.
Tap42GD8900 is rescued by Scer\GAL4ap-md544/Tap42UAS.cCa
Tap42GD8900 is rescued by Scer\GAL4pnr-MD237/Tap42UAS.cCa
Tap42GD8900 is not rescued by Tap42ED.UAS/Scer\GAL4ap-md544
Tap42GD8900 is not rescued by Tap42ED.UAS/Scer\GAL4pnr-MD237
Co-expression of Tap42Scer\UAS.cCa, but not Tap42ED.Scer\UAS, rescues the thorax and wing development phenotypes of flies expressing Tap42GD8900 under the control of Scer\GAL4ap-md544.
Co-expression of Tap42Scer\UAS.cCa, but not Tap42ED.Scer\UAS, rescues the thorax defect and reduced survival of flies expressing Tap42GD8900 under the control of Scer\GAL4pnr-MD237.