FlyBase Allele Report: Dmel\Map205[GD8458]

General Information

Symbol

Dmel\Map205^GD8458

Species

D. melanogaster

Name

FlyBase ID

FBal0207586

Feature type

allele

Associated gene

Dmel\Map205

Associated Insertion(s)

Carried in Construct

P{GD8458}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD8458}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD8458

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Adults expressing Map205^GD8458 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

8458

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Map205^GD8458, Scer\GAL4^CCAP.PP is a suppressor of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4^CCAP.PP, TBPH^UAS.Tag:FLAG

(Vanden Broeck et al., 2013)

Scer\GAL4^nSyb.PU/Map205^GD8458 is a suppressor of lethal - all die before end of pupal stage phenotype of TBPH^Δ142/TBPH^Δ23

(Vanden Broeck et al., 2013)

Phenotype Manifest In

Suppressor of

Statement

Reference

Map205^GD8458, Scer\GAL4^CCAP.PP is a suppressor of peptidergic neuron phenotype of Scer\GAL4^CCAP.PP, TBPH^KK108354

(Vanden Broeck et al., 2013)

Map205^GD8458, Scer\GAL4^CCAP.PP is a suppressor of peptidergic neuron phenotype of Scer\GAL4^CCAP.PP, TBPH^UAS.Tag:FLAG

(Vanden Broeck et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Map205^GD8458 under the control of Scer\GAL4^nSyb.PU suppresses the late pupal lethality seen in TBPH^Δ142/TBPH^Δ23 mutants.

Expression of Map205^GD8458 suppresses the immature wing inflation phenotype seen when TBPH^KK108354 is expressed under the control of Scer\GAL4^nSyb.PU.

Expression of Map205^GD8458 suppresses the immature wing inflation phenotype seen when TBPH^{Scer\UAS.T:Zzzz\FLAG} is expressed under the control of Scer\GAL4^nSyb.PU.

Expression of Map205^GD8458 suppresses the wing inflation phenotype and loss of CCAP/bursicon neurons seen when TBPH^KK108354 is expressed under the control of Scer\GAL4^CCAP.PP.

Expression of Map205^GD8458 suppresses the wing inflation phenotype and loss of CCAP/bursicon neurons seen when TBPH^{Scer\UAS.T:Zzzz\FLAG} is expressed under the control of Scer\GAL4^CCAP.PP.

(Vanden Broeck et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

VDRC

v18402