UASt regulatory sequences drive expression of an inverted repeat.
in individuals expressing CG5003GD11500 under the control of Scer\GAL4elav.PU transheterozygotes, some mushroom body gamma-lobes are present and left unpruned at 18h after puparium formation.
Embryos derived from adults expressing CG5003GD11500 under the control of Scer\GAL4VP16.mat.αTub67C (in combination with a Dicer-2 transgene to enhance RNAi efficiency) leads to early embryonic arrest or delay during the first or second mitotic divisions.
Adults expressing CG5003GD11500 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) can show significantly reduced avoidance of noxious temperature (46[o]C) compared to control flies, depending on the particular P{GD11500} insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 0% or 10-20% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Scer\GAL4elav.PU/CG5003GD11500 partially rescues CG5003UAS.cYa